A tire can be off by only a few grams, but once it reaches highway speeds, that small imbalance creates centrifugal forces strong enough to cause steering vibration, uneven tread wear, suspension Causes of Tire Vibration If your truck is vibrating, dont ignore the tire wear pattern. Uneven tires can absolutely cause vibration especially at highway speeds. When tread wears inconsistently, you get: Irregular tire Causes of Car Vibration: Find Out If Your Car Tyre Is the Cause of Vibration Protyre