Overcoming UTI Recurrence: Tips for Prevention Advanced Urology Institute Does the use of condoms or spermicides contribute to UTIs? We haven't found much scientific research on this topic yet, but people in our community have reported that: Condoms can cause Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex Can Lube Cause UTIs: We Explore if There's a Connection Quanna