Vape Vs E Cigarette E Cigarettes, Vapes, and other Electronic Nicotine Delivery Systems (ENDS) Vaping and the Brain: Effects of Electronic Cigarettes and E Liquid Substances The Journal of Neuropsychiatry and Clinical Neurosciences Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published E Cigarette Side Effects: What Every Vaper Needs to Know