Vaping puts health at risk. Nicotine in e cigarettes is highly addictive. The 101 on e Cigarettes Infographic American Heart Association Toxicity, Chemistry, and Public Health Relevance of Emerging Nicotine Analog Vapes, Pods, and Pouches Chemical Research in Toxicology Vaping is often marketed as a safer alternative to smoking, but many vape products contain nicotine, harmful chemicals, and heavy metals that can harm developing brains and lungs.